Hakone Health Ectoin Serum

New! Ectoin is a natural stress-protection molecule (an extremolyte) known as "nature's bodyguard". It forms a protective hydration shield around skin cells, defending against environmental damage while deeply restoring the skin barrier.

Deep, Long-Lasting Hydration: Ectoin binds moisture at the cellular level to prevent transepidermal water loss (TEWL), providing hydration that lasts up to 48 hours.

Barrier Repair & Strengthening: This serum works to rebuilds compromised skin barriers, helping reduce irritation, flakiness, and sensitivity.

Calms Redness & Inflammation: Ectoin soothes reactive, stressed, or rosacea-prone skin, fast-tracking recovery from harsh weather or active treatments.

Environmental Defense: Shields cells against daily aggressors like UV radiation, blue light, heat, and micro-pollution.

Buffers Potent Actives: Mitigates the drying and irritating side effects of harsh ingredients like retinoids and exfoliants (AHAs/BHAs).

What is Ectoin? 

Hakone Health Ectoin (Tetrahydro-methylpyrimidinecarboxylic acid) is a mild cosmetic active ingredient derived from microbial fermentation.

• 30ml standard portable size, transparent bottle to view residual volume clearly
• Mild clean formula, no artificial-alcohol, no strong synthetic fragrance
• 1% Strength. Strictly tested for daily cosmetic use, gentle for long-term regular care
• Light watery texture, fast penetration, no sticky residue on skin
• Paraben-free. Alcohol-free. Fragrance-free. Cruelty-free.

How to Use

• Clean your face gently with mild cleanser
• Pat toner evenly all-over facial skin
• Drop 2~3 drops of Ectoin Serum onto palm
• Tap and press serum into face & neck until fully absorbed
• Follow with face cream to lock in moisture for longer care

Canadian label may vary from the illustration shown.

Supporting Studies

Ectoine is a natural osmolyte found in extremophilic microorganisms that survives intense environmental stress. Research highlights its potential in dermatology and respiratory health through cellular membrane stabilization.

Topical Ectoine Application in Children and Adults to Treat Inflammatory Diseases Associated with an Impaired Skin Barrier: A Systematic Review. PMCID: PMC8850511.

Ectoine as a multifunctional molecule: biotechnological production and pharmaceutical applications. PMID: 41299111.

The Influence of Ectoine on the Skin Parameters Damaged by a CO2 Laser. Molecules 2025, 30(11), 2470.

Formula Ingredients

This formula contains 1% Ectoin. The full INCI ingredient list is: Water, Glycerin, Propylene Glycol, Betaine, Ectoin, Panthenol, Allantoin, Sodium Hyaluronate, Hydroxyethylcellulose, Carbomer, Triethanolamine, Phenoxyethanol, Ethylhexylglycerin. 

Ships from Canada.